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Mesothelioma and Other Asbestos Related Cancers People who have a history of exposure to asbestos are at risk of developing several types of cancer that include mesothelioma. These cancers have a long latency period, meaning symptoms don't manifest until years after exposure. The risk of developing pleural and peritoneal msothelioma diminishes after first exposure. The evidence is drawn from six occupational cohort studies and two residential cohorts with long-term follow-up. What is Mesothelioma? Mesothelioma refers to cancer of the internal organs' lining that include the lungs (pleural mesothelioma) or abdomen (peritoneal mesothelioma) or heart (pericardial mesothelioma). It is a rare and severe disease that typically begins in the lining of the chest cavity. However, it could also affect the lining in the stomach and other areas of your body. Asbestos is the most significant cause of mesothelioma. The cancer usually doesn't show up until decades after exposure. The people who are exposed asbestos at work have a greater chance of developing cancer than others. Asbestos fibers can be breathed in or swallowed and cling to the organ's lining. The fibers irritate the lining of the organ and cause abnormal cells to multiply, leading to tumors. Symptoms usually do not appear until a person has developed mesothelioma with advanced stage. The most frequent exposure to asbestos occurs in jobs in the industrial sector in which workers handled the material or worked in proximity to it. Asbestos was employed in construction, shipbuilding auto repair, shipbuilding and other trades. Veterans who served in the military are at a higher risk for mesothelioma, as asbestos was extensively used on ships and bases. Patients with a exposure to asbestos are required to undergo regular checks, and should be alert for any unusual symptoms. If pennsylvania asbestos attorneys suspects mesothelioma, they may conduct imaging tests like CT scans, MRI or PET scans to check for tumors and determine whether they have developed. They may also perform a physical exam and ask about a patient's asbestos exposure background. Certain mesothelioma cases can be linked to genetic changes. So, certain patients could benefit from genetic testing. Risk Factors The exposure to asbestos is the main mesothelioma-related risk factor. Asbestos, a mineral composed of fibers, is resistant to heat and is strong. Asbestos was utilized in a variety of manufacturing and construction materials, such as insulation, brakes and shingles. When asbestos is disturbed, it produces dust that can be inhaled or swallowed. This can cause irritation to mesothelium, which could eventually lead to mesothelioma. People with an history of occupational asbestos exposure are at the most risk of mesothelioma. This includes people who worked in industries like shipbuilding, mining, construction and automotive repair. Veterans of the military are also at risk, as many branches of the military utilized asbestos-based products. Other factors that increase the risk of mesothelioma is a family history of asbestos exposure and previous treatment for chest cancer with radiation. The type of mesothelioma detected also has a major impact on the risk. Pleural mesothelioma is the most prevalent form and typically affects the lungs. Other mesothelioma types include peritoneal (pericardial) testsicular, testicular, and the peritoneal. In general, the risk of mesothelioma increases with the third to fourth power of latency – which is the length of time it takes for someone to be diagnosed. The rate of pleural cancer shows an apparent flattening after 40 years. Both peritoneal and pericardial mesothelioma show the same trend. Individuals who have exposure to asbestos – such as living near to an asbestos plant or eating contaminated household products are also at higher risk for mesothelioma. In a study of six cities, people who were exposed to asbestos in this manner were at a higher risk of mesothelioma than those who only had occupational exposure. Signs and symptoms Malignant mesothelioma affects the cellular that surrounds internal organs. It is most often found in the lining of the lungs (pleura) and abdomen (peritoneum). Mesothelioma can also develop in the lining around the testicles or heart. It is a rare type of cancer, and most patients diagnosed with mesothelioma worked in jobs where they were exposed to asbestos. It can take decades for symptoms of mesothelioma to manifest, and the disease is not curable. Asbestos is a group minerals that have microscopic fibers and are impervious to heat, chemicals, and fire. It is widely used in many industries, such as shipbuilding, manufacturing, construction and more. Exposure to asbestos may cause mesothelioma as asbestos fibers can become stuck in tissues lining and protect organs. This causes irritation and damages to cells. This can cause tumors to expand and eventually turn into cancerous. The most common form of mesothelioma occurs in the lining (pleura) of the lung. It can also develop in the lining of the testicles or heart or in the abdominal lining (peritoneum). Mesothelioma can also be spread to lymph nodes and cause swelling of the lymph nodes. The majority of people diagnosed mesothelioma suffer from a history of exposure to asbestos and also suffer from other diseases like chronic pulmonary disease. Mesothelioma symptoms may be similar to other diseases, so you should seek out a physician when any recurring or alarming symptoms persist. Doctors will ask about your previous exposure to asbestos and may perform an examination. They may also order imaging scans or blood tests of your abdomen and chest. They can detect any growth in the lung's lining, or the fluid that is leaking out of the space between your lungs and the chest wall. Diagnosis Asbestos fibers that become stuck on the body can cause harm and may eventually grow into cancerous tumors. Asbestos-related cancers can form in a variety of organs and tissues. Each kind of cancer can be diagnosed with a different test. Mesothelioma is found in the lining of the chest cavity and the lungs (pleura), the stomach membranes (peritoneum) or around the reproductive organs and the heart. The first step in diagnosing mesothelioma is to talk to their doctor about their history with asbestos exposure and the symptoms they've experienced. Doctors also conduct a physical examination and order basic tests like blood tests to determine how well the lungs function. X-rays or CT scans can aid doctors in identifying the affected area more clearly. In certain instances doctors will perform a test of pleural fluid to determine if mesothelioma may be responsible for the buildup of fluid. The pleural effusion may be a symptom of pleural mesothelioma, peritoneal mesothelioma or a rarer type of mesothelioma known as biphasic or mixed mesothelioma. Mesothelioma is often misdiagnosed as the symptoms are similar to those of other diseases and conditions. The most common symptoms include difficulty breathing and chest pain. Pleural mesothelioma may also cause a cough, chest tightness and fatigue. Peritoneal mesothelioma can cause abdominal pain swelling and distension. Testicular mesothelioma can manifest as a painful, itchy lump on the testicles. Researchers are studying the proteins in the blood to develop methods to detect mesothelioma in the early stages. They are also researching a number other tests and procedures that could improve the accuracy of diagnosis. This includes mesothelioma scans and MRIs. They are also researching genetic mutations and how to determine if someone is at risk for mesothelioma by examining their family history. Treatment Asbestos exposure is the primary risk factor for mesothelioma. People who have worked with asbestos in the past, particularly for long periods of time, or in high-risk jobs such as construction, shipbuilding, electrical work military service and auto repair, are at increased risk. Exposure to asbestos causes mesothelioma when fibers get stuck in tissue that lines and protects vital organs. The fibers cause DNA damage and irritation to the mesothelium, which causes cancerous cells to grow. Mesothelioma symptoms generally do not appear until decades after exposure. Symptoms differ depending on the type of mesothelioma and where it is found within the body. Most mesothelioma patients have the lung lining (pleural) but it can also affect the stomach's lining, the heart and testicles. Mesothelioma staging helps doctors determine treatment options. The disease is categorized as stage I through IV with stages I and II being the earliest stages and most treatable. Stage III and IV are the more advanced stages of cancer that are more difficult to treat, however there are many treatment options available. Pleural mesothelioma, the most common form of the disease and affects the lining of the lungs and chest wall, as well as the abdomen. The majority of cases of pleural msothelioma result from asbestos exposure while working. Most likely asbestos was inhaled via airborne particles or consumed via food items. Other risk factors include mesothelioma-related family history, genetic mutations, and previous radiation therapy for another condition. It is important to consult an expert if you experience symptoms of mesothelioma or were exposed to asbestos. You could also benefit from genetic counseling. A mesothelioma specialist can assist you in filing a lawsuit against companies that have wrongfully used asbestos in their everyday products.